Ex vivo pleural effusion cultures to study chimeric antigen receptor T cell cytotoxicity in an immunocompetent environment

Current in vitro and in vivo assays used to study immunotherapeutic interventions lack human immune components that mimic the tumor microenvironment to investigate drug potency and limitations of efficacy. Herein, we describe an ex vivo pleural effusion culture (ePEC) assay, using malignant pleural-...

Descripción completa

Detalles Bibliográficos
Autores principales: Tano, Zachary E., Kiesgen, Stefan, Chintala, Navin K., Dozier, Jordan, Quach, Hue Tu, Messinger, John, Tan, Kay See, Adusumilli, Prasad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694486/
https://www.ncbi.nlm.nih.gov/pubmed/37875122
http://dx.doi.org/10.1016/j.crmeth.2023.100622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694486/
https://www.ncbi.nlm.nih.gov/pubmed/37875122
http://dx.doi.org/10.1016/j.crmeth.2023.100622

Ejemplares similares