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Accessible high-throughput single-cell whole-genome sequencing with paired chromatin accessibility

Single-cell whole-genome sequencing (scWGS) enables the assessment of genome-level molecular differences between individual cells with particular relevance to genetically diverse systems like solid tumors. The application of scWGS was limited due to a dearth of accessible platforms capable of produc...

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Detalles Bibliográficos
Autores principales: Queitsch, Konstantin, Moore, Travis W., O’Connell, Brendan L., Nichols, Ruth V., Muschler, John L., Keith, Dove, Lopez, Charles, Sears, Rosalie C., Mills, Gordon B., Yardımcı, Galip Gürkan, Adey, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694488/
https://www.ncbi.nlm.nih.gov/pubmed/37918402
http://dx.doi.org/10.1016/j.crmeth.2023.100625