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Deep mutational scanning of proteins in mammalian cells

Protein mutagenesis is essential for unveiling the molecular mechanisms underlying protein function in health, disease, and evolution. In the past decade, deep mutational scanning methods have evolved to support the functional analysis of nearly all possible single-amino acid changes in a protein of...

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Detalles Bibliográficos
Autores principales: Maes, Stefanie, Deploey, Nick, Peelman, Frank, Eyckerman, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694495/
https://www.ncbi.nlm.nih.gov/pubmed/37963462
http://dx.doi.org/10.1016/j.crmeth.2023.100641