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Natural infection by Zika virus but not DNA vaccination consistently elicits antibodies that compete with two potently neutralising monoclonal antibodies targeting distinct epitopes

BACKGROUND: Autochthonous transmission of Zika virus (ZIKV) has been reported in 87 countries since 2015. Although most infections are mild, there is risk of Guillain-Barré syndrome and adverse pregnancy outcomes. Vaccines are urgently needed to prevent Zika, but sufficient understanding of humoral...

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Detalles Bibliográficos
Autores principales: Smith, Teresa C., Espinoza, Daniel O., Zhu, Yerun, Cardona-Ospina, Jaime A., Bowman, Natalie M., Becker-Dreps, Sylvia, Rouphael, Nadine, Rodriguez-Morales, Alfonso J., Bucardo, Filemon, Edupuganti, Srilatha, Premkumar, Lakshmanane, Mulligan, Mark J., de Silva, Aravinda M., Collins, Matthew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694573/
https://www.ncbi.nlm.nih.gov/pubmed/37983984
http://dx.doi.org/10.1016/j.ebiom.2023.104875