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A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation
Scaffold proteins help mediate interactions between protein partners, often to optimize intracellular signaling. Herein, we use comparative, biochemical, biophysical, molecular, and cellular approaches to investigate how the scaffold protein NEMO contributes to signaling in the NF-κB pathway. Compar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694592/ https://www.ncbi.nlm.nih.gov/pubmed/37890781 http://dx.doi.org/10.1016/j.jbc.2023.105396 |