A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation

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Scaffold proteins help mediate interactions between protein partners, often to optimize intracellular signaling. Herein, we use comparative, biochemical, biophysical, molecular, and cellular approaches to investigate how the scaffold protein NEMO contributes to signaling in the NF-κB pathway. Compar...

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Detalles Bibliográficos
Autores principales: DiRusso, Christopher J., DeMaria, Anthony M., Wong, Judy, Wang, Wei, Jordanides, Jack J., Whitty, Adrian, Allen, Karen N., Gilmore, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694592/
https://www.ncbi.nlm.nih.gov/pubmed/37890781
http://dx.doi.org/10.1016/j.jbc.2023.105396

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