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Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency

Rabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid cytotoxicity of first-generation (ΔG) vectors limits their...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Sullivan, Heather A., Zhu, Mulangma, Lea, Nicholas E., Lavin, Thomas K., Fu, Xin, Matsuyama, Makoto, Hou, YuanYuan, Feng, Guoping, Wickersham, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694603/
https://www.ncbi.nlm.nih.gov/pubmed/37989085
http://dx.doi.org/10.1016/j.crmeth.2023.100644