Cargando…

Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas

The isocitrate dehydrogenase (IDH) gene is recurrently mutated in adult diffuse gliomas. IDH-mutant gliomas are categorized into oligodendrogliomas and astrocytomas, each with unique pathological features. Here, we use single-nucleus RNA and ATAC sequencing to compare the molecular heterogeneity of...

Descripción completa

Detalles Bibliográficos
Autores principales: Blanco-Carmona, Enrique, Narayanan, Ashwin, Hernandez, Inmaculada, Nieto, Juan C., Elosua-Bayes, Marc, Sun, Xueyuan, Schmidt, Claudia, Pamir, Necmettin, Özduman, Koray, Herold-Mende, Christel, Pagani, Francesca, Cominelli, Manuela, Taranda, Julian, Wick, Wolfgang, von Deimling, Andreas, Poliani, Pietro Luigi, Rehli, Michael, Schlesner, Matthias, Heyn, Holger, Turcan, Şevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694621/
https://www.ncbi.nlm.nih.gov/pubmed/37883975
http://dx.doi.org/10.1016/j.xcrm.2023.101249