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Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas
The isocitrate dehydrogenase (IDH) gene is recurrently mutated in adult diffuse gliomas. IDH-mutant gliomas are categorized into oligodendrogliomas and astrocytomas, each with unique pathological features. Here, we use single-nucleus RNA and ATAC sequencing to compare the molecular heterogeneity of...
Autores principales: | Blanco-Carmona, Enrique, Narayanan, Ashwin, Hernandez, Inmaculada, Nieto, Juan C., Elosua-Bayes, Marc, Sun, Xueyuan, Schmidt, Claudia, Pamir, Necmettin, Özduman, Koray, Herold-Mende, Christel, Pagani, Francesca, Cominelli, Manuela, Taranda, Julian, Wick, Wolfgang, von Deimling, Andreas, Poliani, Pietro Luigi, Rehli, Michael, Schlesner, Matthias, Heyn, Holger, Turcan, Şevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694621/ https://www.ncbi.nlm.nih.gov/pubmed/37883975 http://dx.doi.org/10.1016/j.xcrm.2023.101249 |
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