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ABHD12 contributes to tumorigenesis and sorafenib resistance by preventing ferroptosis in hepatocellular carcinoma

Sorafenib induces ferroptosis, making it a useful treatment against advanced liver hepatocellular carcinoma (LIHC). However, sorafenib resistance is extremely common among LIHC patients. Here, we used a comprehensive approach to investigate the effects of ABHD12, which regulates tumorigenesis and so...

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Detalles Bibliográficos
Autores principales: Cai, Mengxing, Luo, Jingwen, Yang, Chunxiu, Yang, Xiaopeng, Zhang, Cheng, Ma, Lixin, Cheng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694648/
http://dx.doi.org/10.1016/j.isci.2023.108340