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Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis

The choroid plexus (CP) plays a key role in remotely controlling brain function in health, aging, and disease. Here, we report that CP epithelial cells express the brain-specific cholesterol 24-hydroxylase (CYP46A1) and that its levels are decreased under different mouse and human brain conditions,...

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Detalles Bibliográficos
Autores principales: Tsitsou-Kampeli, Afroditi, Suzzi, Stefano, Kenigsbuch, Mor, Satomi, Akisawa, Strobelt, Romano, Singer, Oded, Feldmesser, Ester, Purnapatre, Maitreyee, Colaiuta, Sarah Phoebeluc, David, Eyal, Cahalon, Liora, Hahn, Oliver, Wyss-Coray, Tony, Shaul, Yosef, Amit, Ido, Schwartz, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694665/
https://www.ncbi.nlm.nih.gov/pubmed/37944529
http://dx.doi.org/10.1016/j.xcrm.2023.101278