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Personalized drug screening in patient-derived organoids of biliary tract cancer and its clinical application

Patients with biliary tract cancer (BTC) show different responses to chemotherapy, and there is no effective way to predict chemotherapeutic response. We have generated 61 BTC patient-derived organoids (PDOs) from 82 tumors (74.4%) that show similar histological and genetic characteristics to the co...

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Detalles Bibliográficos
Autores principales: Ren, Xiaoxue, Huang, Mingle, Weng, Weixiang, Xie, Yubin, Wu, Yifan, Zhu, Shenghua, Zhang, Ying, Li, Dongming, Lai, Jiaming, Shen, Shunli, Lin, Jie, Kuang, Ming, Li, Xiaoxing, Yu, Jun, Xu, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694672/
https://www.ncbi.nlm.nih.gov/pubmed/37944531
http://dx.doi.org/10.1016/j.xcrm.2023.101277