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Enhanced osteoblastic differentiation of parietal bone in a novel murine model of mucopolysaccharidosis type II

Mucopolysaccharidosis type II (MPS II, OMIM 309900) is an X-linked disorder caused by a deficiency of lysosomal enzyme iduronate-2-sulfatase (IDS). The clinical manifestations of MPS II involve cognitive decline, bone deformity, and visceral disorders. These manifestations are closely associated wit...

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Detalles Bibliográficos
Autores principales: Yamazaki, Narutoshi, Ohira, Mari, Takada, Shuji, Ohtake, Akira, Onodera, Masafumi, Nakanishi, Mahito, Okuyama, Torayuki, Mashima, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694741/
http://dx.doi.org/10.1016/j.ymgmr.2023.101021