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Immune imprinting as a barrier to effective COVID-19 vaccines
Wang and colleagues show that immune imprinting impairs neutralizing antibody titers for bivalent mRNA vaccination against SARS-CoV-2 Omicron subvariants. Imprinting from three doses of monovalent vaccine can be alleviated by BA.5 or BQ-lineage breakthrough infection but not by a bivalent booster.(1...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694758/ https://www.ncbi.nlm.nih.gov/pubmed/37992689 http://dx.doi.org/10.1016/j.xcrm.2023.101291 |
| _version_ | 1785153449272279040 |
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| author | Faraone, Julia N. Liu, Shan-Lu |
| author_facet | Faraone, Julia N. Liu, Shan-Lu |
| author_sort | Faraone, Julia N. |
| collection | PubMed |
| description | Wang and colleagues show that immune imprinting impairs neutralizing antibody titers for bivalent mRNA vaccination against SARS-CoV-2 Omicron subvariants. Imprinting from three doses of monovalent vaccine can be alleviated by BA.5 or BQ-lineage breakthrough infection but not by a bivalent booster.(1) |
| format | Online Article Text |
| id | pubmed-10694758 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-106947582023-12-05 Immune imprinting as a barrier to effective COVID-19 vaccines Faraone, Julia N. Liu, Shan-Lu Cell Rep Med Preview Wang and colleagues show that immune imprinting impairs neutralizing antibody titers for bivalent mRNA vaccination against SARS-CoV-2 Omicron subvariants. Imprinting from three doses of monovalent vaccine can be alleviated by BA.5 or BQ-lineage breakthrough infection but not by a bivalent booster.(1) Elsevier 2023-11-21 /pmc/articles/PMC10694758/ /pubmed/37992689 http://dx.doi.org/10.1016/j.xcrm.2023.101291 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Preview Faraone, Julia N. Liu, Shan-Lu Immune imprinting as a barrier to effective COVID-19 vaccines |
| title | Immune imprinting as a barrier to effective COVID-19 vaccines |
| title_full | Immune imprinting as a barrier to effective COVID-19 vaccines |
| title_fullStr | Immune imprinting as a barrier to effective COVID-19 vaccines |
| title_full_unstemmed | Immune imprinting as a barrier to effective COVID-19 vaccines |
| title_short | Immune imprinting as a barrier to effective COVID-19 vaccines |
| title_sort | immune imprinting as a barrier to effective covid-19 vaccines |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694758/ https://www.ncbi.nlm.nih.gov/pubmed/37992689 http://dx.doi.org/10.1016/j.xcrm.2023.101291 |
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