Phosphatidylserine synthesis controls oncogenic B cell receptor signaling in B cell lymphoma

Cancer cells harness lipid metabolism to promote their own survival. We screened 47 cancer cell lines for survival dependency on phosphatidylserine (PS) synthesis using a PS synthase 1 (PTDSS1) inhibitor and found that B cell lymphoma is highly dependent on PS. Inhibition of PTDSS1 in B cell lymphom...

Descripción completa

Detalles Bibliográficos
Autores principales: Omi, Jumpei, Kato, Taiga, Yoshihama, Yohei, Sawada, Koki, Kono, Nozomu, Aoki, Junken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694799/
https://www.ncbi.nlm.nih.gov/pubmed/38048228
http://dx.doi.org/10.1083/jcb.202212074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694799/
https://www.ncbi.nlm.nih.gov/pubmed/38048228
http://dx.doi.org/10.1083/jcb.202212074

Ejemplares similares