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Replenishing NAD(+) content reduces aspects of striated muscle disease in a dog model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in DMD gene and loss of the protein dystrophin, which ultimately leads to myofiber membrane fragility and necrosis, with eventual muscle atrophy and contractures. Affected boys typically die in their second or third decade...

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Detalles Bibliográficos
Autores principales: Cardoso, Déborah, Barthélémy, Inès, Blot, Stéphane, Muchir, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694913/
https://www.ncbi.nlm.nih.gov/pubmed/38044436
http://dx.doi.org/10.1186/s13395-023-00328-w