Targeting the epigenome to reinvigorate T cells for cancer immunotherapy

Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) has revolutionized the field of cancer treatment; however, ICI efficacy is constrained by progressive dysfunction of CD8(+) tumor-infiltrating lymphocytes (TILs), which is termed T cell exhaustion. This process is driven by diverse extri...

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Detalles Bibliográficos
Autores principales: Xiong, Dian, Zhang, Lu, Sun, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694991/
https://www.ncbi.nlm.nih.gov/pubmed/38044445
http://dx.doi.org/10.1186/s40779-023-00496-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694991/
https://www.ncbi.nlm.nih.gov/pubmed/38044445
http://dx.doi.org/10.1186/s40779-023-00496-2

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