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Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) has revolutionized the field of cancer treatment; however, ICI efficacy is constrained by progressive dysfunction of CD8(+) tumor-infiltrating lymphocytes (TILs), which is termed T cell exhaustion. This process is driven by diverse extri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694991/ https://www.ncbi.nlm.nih.gov/pubmed/38044445 http://dx.doi.org/10.1186/s40779-023-00496-2 |