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Ascorbate protects human kidney organoids from damage induced by cell-free hemoglobin

Sepsis-associated acute kidney injury is associated with high morbidity and mortality in critically ill patients. Cell-free hemoglobin (CFH) is released into the circulation of patients with severe sepsis and the levels of CFH are independently associated with mortality. CFH treatment increased cyto...

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Detalles Bibliográficos
Autores principales: Bejoy, Julie, Farry, Justin M., Qian, Eddie S., Dearing, Curtis H., Ware, Lorraine B., Bastarache, Julie A., Woodard, Lauren E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695115/
https://www.ncbi.nlm.nih.gov/pubmed/37942584
http://dx.doi.org/10.1242/dmm.050342