Rapamycin Exacerbates Staphylococcus aureus Pneumonia by Inhibiting mTOR-RPS6 in Macrophages

PURPOSE: This study aimed to explore the effect of Rapamycin (Rapa) in Staphylococcus aureus (S. aureus) pneumonia and clarify its possible mechanism. METHODS: We investigated the effects of Rapa on S. aureus pneumonia in mouse models and in macrophages cultured in vitro. Two possible mechanisms wer...

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Detalles Bibliográficos
Autores principales: Yu, Fang-Yi, Zheng, Kua, Wu, Yin-Fang, Gao, Shen-Wei, Weng, Qing-Yu, Zhu, Chen, Wu, Yan-Ping, Li, Miao, Qin, Zhong-Nan, Lou, Jia-Fei, Chen, Zhi-Hua, Ying, Song-Min, Shen, Hua-Hao, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695130/
http://dx.doi.org/10.2147/JIR.S434483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695130/
http://dx.doi.org/10.2147/JIR.S434483

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