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Neural network models for sequence-based TCR and HLA association prediction

T cells rely on their T cell receptors (TCRs) to discern foreign antigens presented by human leukocyte antigen (HLA) proteins. The TCRs of an individual contain a record of this individual’s past immune activities, such as immune response to infections or vaccines. Mining the TCR data may recover us...

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Detalles Bibliográficos
Autores principales: Liu, Si, Bradley, Philip, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695368/
https://www.ncbi.nlm.nih.gov/pubmed/37983288
http://dx.doi.org/10.1371/journal.pcbi.1011664