Cargando…

Neural network models for sequence-based TCR and HLA association prediction

Mostrar otras versiones (1)

T cells rely on their T cell receptors (TCRs) to discern foreign antigens presented by human leukocyte antigen (HLA) proteins. The TCRs of an individual contain a record of this individual’s past immune activities, such as immune response to infections or vaccines. Mining the TCR data may recover us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Si, Bradley, Philip, Sun, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695368/ https://www.ncbi.nlm.nih.gov/pubmed/37983288 http://dx.doi.org/10.1371/journal.pcbi.1011664

Ejemplares similares

Neural Network Models for Sequence-Based TCR and HLA Association Prediction
por: Liu, Si, et al.
Publicado: (2023)

Naive and memory T cells TCR–HLA-binding prediction
por: Glazer, Neta, et al.
Publicado: (2022)

TCR meta-clonotypes for biomarker discovery with tcrdist3: identification of public, HLA-restricted SARS-CoV-2 associated TCR features
por: Mayer-Blackwell, Koshlan, et al.
Publicado: (2021)

Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival
por: Richard, Guilhem, et al.
Publicado: (2021)

Structural basis of the TCR-pHLA complex provides insights into the unconventional recognition of CDR3β in TCR cross-reactivity and alloreactivity
por: San, Dan, et al.
Publicado: (2022)

Binding of TCR Multimers and a TCR-Like Antibody with Distinct Fine-Specificities Is Dependent on the Surface Density of HLA Complexes
por: Low, Jianrong L., et al.
Publicado: (2012)

NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data
por: Montemurro, Alessandro, et al.
Publicado: (2021)

Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
por: Dillard, Pierre, et al.
Publicado: (2021)

TCR mimic compounds for pHLA targeting with high potency modalities in oncology
por: Gerber, Hans-Peter, et al.
Publicado: (2022)

Simultaneous editing of TCR, HLA-I/II and HLA-E resulted in enhanced universal CAR-T resistance to allo-rejection
por: Li, Wuling, et al.
Publicado: (2022)

NetTCR-2.1: Lessons and guidance on how to develop models for TCR specificity predictions
por: Montemurro, Alessandro, et al.
Publicado: (2022)

Modeling the Ternary Complex TCR-Vβ/CollagenII(261–273)/HLA-DR4 Associated with Rheumatoid Arthritis
por: De Rosa, Maria Cristina, et al.
Publicado: (2010)

Major TCR Repertoire Perturbation by Immunodominant HLA-B(*)44:03-Restricted CMV-Specific T Cells
por: Attaf, Meriem, et al.
Publicado: (2018)

Identification and characterization of heteroclitic peptides in TCR-binding positions with improved HLA-binding efficacy
por: Cavalluzzo, Beatrice, et al.
Publicado: (2021)

A Pan-Specific GRU-Based Recurrent Neural Network for Predicting HLA-I-Binding Peptides
por: Heng, Yu, et al.
Publicado: (2020)

TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs
por: Mayer-Blackwell, Koshlan, et al.
Publicado: (2021)

Membrane fusogenic nanoparticle‐based HLA‐peptide‐addressing universal T cell receptor‐engineered T (HAUL TCR‐T) cell therapy in solid tumor
por: Xu, Ruihan, et al.
Publicado: (2023)

ATM-TCR: TCR-Epitope Binding Affinity Prediction Using a Multi-Head Self-Attention Model
por: Cai, Michael, et al.
Publicado: (2022)

Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs
por: Springer, Ido, et al.
Publicado: (2020)

Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis
por: Tang, Bo, et al.
Publicado: (2014)

TCR sequencing: applications in immuno-oncology research
por: Sanromán, Á.F., et al.
Publicado: (2023)

Hybrid gMLP model for interaction prediction of MHC-peptide and TCR
por: Zhang, Lichao, et al.
Publicado: (2023)

Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control
por: Johanna, Inez, et al.
Publicado: (2021)

Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing
por: Lee, Edward S., et al.
Publicado: (2017)

A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires
por: Tanno, Hidetaka, et al.
Publicado: (2020)

TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets
por: Straetemans, Trudy, et al.
Publicado: (2012)

An artificial neural network‐based model to predict chronic kidney disease in aged cats
por: Biourge, Vincent, et al.
Publicado: (2020)

Targeting KRAS(G12V) mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors
por: Ai, Qi, et al.
Publicado: (2023)

CD8 T cell function and cross-reactivity explored by stepwise increased peptide-HLA versus TCR affinity
por: Baumgaertner, Petra, et al.
Publicado: (2022)

Prediction of MoRFs based on sequence properties and convolutional neural networks
por: He, Hao, et al.
Publicado: (2021)

Potential of TCR sequencing in graft-versus-host disease
por: Goel, Manisha, et al.
Publicado: (2022)

T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones: tumor-infiltrating lymphocytes overexpress in vivo the TCR beta chain sequence used by an HLA-A2- restricted and melanocyte-lineage-specific CTL clone
Publicado: (1993)

Pre-TCRα and TCRα Are Not Interchangeable Partners of TCRβ during T Lymphocyte Development
por: Borowski, Christine, et al.
Publicado: (2004)

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain
por: Kirchgessner, Henning, et al.
Publicado: (2001)

Sequence-based drug-target affinity prediction using weighted graph neural networks
por: Jiang, Mingjian, et al.
Publicado: (2022)

TCR Coexpression Signature Predicts Immunotherapy Resistance in NSCLC
por: Wang, Yuntao, et al.
Publicado: (2022)

Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
por: Liu, Xin, et al.
Publicado: (2022)

DeepSeqPan, a novel deep convolutional neural network model for pan-specific class I HLA-peptide binding affinity prediction
por: Liu, Zhonghao, et al.
Publicado: (2019)

Prediction of Labor Unemployment Based on Time Series Model and Neural Network Model
por: Liu, Xitao, et al.
Publicado: (2022)

TCR–pMHC bond conformation controls TCR ligand discrimination
por: Sasmal, Dibyendu K., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vp5bdvdioh93rl8mtq1ktcc8io