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SAD-1 kinase controls presynaptic phase separation by relieving SYD-2/Liprin-α autoinhibition

Neuronal development orchestrates the formation of an enormous number of synapses that connect the nervous system. In developing presynapses, the core active zone structure has been found to assemble through liquid–liquid phase separation. Here, we find that the phase separation of Caenorhabditis el...

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Detalles Bibliográficos
Autores principales: McDonald, Nathan A., Tao, Li, Dong, Meng-Qiu, Shen, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695385/
https://www.ncbi.nlm.nih.gov/pubmed/38048304
http://dx.doi.org/10.1371/journal.pbio.3002421