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Identifying promoter sequence architectures via a chunking-based algorithm using non-negative matrix factorisation

Core promoters are stretches of DNA at the beginning of genes that contain information that facilitates the binding of transcription initiation complexes. Different functional subsets of genes have core promoters with distinct architectures and characteristic motifs. Some of these motifs inform the...

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Detalles Bibliográficos
Autores principales: Nikumbh, Sarvesh, Lenhard, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695386/
https://www.ncbi.nlm.nih.gov/pubmed/37983292
http://dx.doi.org/10.1371/journal.pcbi.1011491