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A disease associated mutant reveals how Ltv1 orchestrates RP assembly and rRNA folding of the small ribosomal subunit head

Ribosomes are complex macromolecules assembled from 4 rRNAs and 79 ribosomal proteins (RPs). Their assembly is organized in a highly hierarchical manner, which is thought to avoid dead-end pathways, thereby enabling efficient assembly of ribosomes in the large quantities needed for healthy cellular...

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Detalles Bibliográficos
Autores principales: Blomqvist, Ebba K., Huang, Haina, Karbstein, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695388/
https://www.ncbi.nlm.nih.gov/pubmed/37910572
http://dx.doi.org/10.1371/journal.pgen.1010862