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Direct and biologically significant interactions of human herpesvirus 8 interferon regulatory factor 1 with STAT3 and Janus kinase TYK2

Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that target cellular IRFs and/or other innate-immune and stress signaling regulators and suppress the cellular response to viral infection and replication. For vIRF-1, cellular protein targets include IRFs, p53, p53...

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Detalles Bibliográficos
Autores principales: Yang, Zunlin, Xiang, Qiwang, Nicholas, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695398/
https://www.ncbi.nlm.nih.gov/pubmed/37983265
http://dx.doi.org/10.1371/journal.ppat.1011806