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Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein

SARS-CoV-2 spike protein plays a key role in mediating viral entry and inducing host immune responses. It can adopt either an open or closed conformation based on the position of its receptor-binding domain (RBD). It is yet unclear what causes these conformational changes or how they influence the s...

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Detalles Bibliográficos
Autores principales: Geng, Qibin, Wan, Yushun, Hsueh, Fu-Chun, Shang, Jian, Ye, Gang, Bu, Fan, Herbst, Morgan, Wilkens, Rowan, Liu, Bin, Li, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695562/
https://www.ncbi.nlm.nih.gov/pubmed/37991488
http://dx.doi.org/10.7554/eLife.74060