Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance

Drug resistance remains a major obstacle to malaria control and eradication efforts, necessitating the development of novel therapeutic strategies to treat this disease. Drug combinations based on collateral sensitivity, wherein resistance to one drug causes increased sensitivity to the partner drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Mandt, Rebecca EK, Luth, Madeline R, Tye, Mark A, Mazitschek, Ralph, Ottilie, Sabine, Winzeler, Elizabeth A, Lafuente-Monasterio, Maria Jose, Gamo, Francisco Javier, Wirth, Dyann F, Lukens, Amanda K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695565/
https://www.ncbi.nlm.nih.gov/pubmed/37737220
http://dx.doi.org/10.7554/eLife.85023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695565/
https://www.ncbi.nlm.nih.gov/pubmed/37737220
http://dx.doi.org/10.7554/eLife.85023

Ejemplares similares