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Rational design peptide inhibitors of Cyclophilin D as a potential treatment for acute pancreatitis

Cyclophilin D (CypD) is a mitochondrial matrix peptidyl prolidase that regulates the mitochondrial permeability transition pore. Inhibition of CypD was suggested as a therapeutic strategy for acute pancreatitis. Peptide inhibitors emerged as novel binding ligand for blocking receptor activity. In th...

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Detalles Bibliográficos
Autores principales: Li, Yuehong, Liu, Ting, Lai, Xiaoyan, Xie, Huifang, Tang, Heng, Wu, Shuangchan, Li, Yongshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695616/
http://dx.doi.org/10.1097/MD.0000000000036188