Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease

Lon is a widely distributed AAA+ (ATPases associated with diverse cellular activities) protease known for degrading poorly folded and damaged proteins and is often classified as a weak protein unfoldase. Here, using a Lon-degron pair from Mesoplasma florum (MfLon and MfssrA, respectively), we perfor...

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Detalles Bibliográficos
Autores principales: Kasal, Meghann R., Kotamarthi, Hema Chandra, Johnson, Madeline M., Stephens, Hannah M., Lang, Matthew J., Sauer, Robert T., Baker, Tania A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695633/
https://www.ncbi.nlm.nih.gov/pubmed/37660294
http://dx.doi.org/10.1016/j.celrep.2023.113061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695633/
https://www.ncbi.nlm.nih.gov/pubmed/37660294
http://dx.doi.org/10.1016/j.celrep.2023.113061

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