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Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease
Lon is a widely distributed AAA+ (ATPases associated with diverse cellular activities) protease known for degrading poorly folded and damaged proteins and is often classified as a weak protein unfoldase. Here, using a Lon-degron pair from Mesoplasma florum (MfLon and MfssrA, respectively), we perfor...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695633/ https://www.ncbi.nlm.nih.gov/pubmed/37660294 http://dx.doi.org/10.1016/j.celrep.2023.113061 |