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A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase

There are two anticonvertase antibody populations—Nephritic Factors which cause complement dysregulation and C3CAbs which do not. C3CAbs are highly prevalent in the healthy adult population (>95% prevalence). C3CAbs suggest a direction of study to determine the origin of Nephritic Factors.

Detalles Bibliográficos
Autores principales: Culek, Christopher T., Nester, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695638/
https://www.ncbi.nlm.nih.gov/pubmed/37907434
http://dx.doi.org/10.34067/KID.0000000000000260