A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase

There are two anticonvertase antibody populations—Nephritic Factors which cause complement dysregulation and C3CAbs which do not. C3CAbs are highly prevalent in the healthy adult population (>95% prevalence). C3CAbs suggest a direction of study to determine the origin of Nephritic Factors.

Detalles Bibliográficos
Autores principales: Culek, Christopher T., Nester, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695638/
https://www.ncbi.nlm.nih.gov/pubmed/37907434
http://dx.doi.org/10.34067/KID.0000000000000260
_version_ 1785153610505519104
author Culek, Christopher T.
Nester, Carla M.
author_facet Culek, Christopher T.
Nester, Carla M.
author_sort Culek, Christopher T.
collection PubMed
description There are two anticonvertase antibody populations—Nephritic Factors which cause complement dysregulation and C3CAbs which do not. C3CAbs are highly prevalent in the healthy adult population (>95% prevalence). C3CAbs suggest a direction of study to determine the origin of Nephritic Factors.
format Online
Article
Text
id pubmed-10695638
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher American Society of Nephrology
record_format MEDLINE/PubMed
spelling pubmed-106956382023-12-05 A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase Culek, Christopher T. Nester, Carla M. Kidney360 Brief Communication There are two anticonvertase antibody populations—Nephritic Factors which cause complement dysregulation and C3CAbs which do not. C3CAbs are highly prevalent in the healthy adult population (>95% prevalence). C3CAbs suggest a direction of study to determine the origin of Nephritic Factors. American Society of Nephrology 2023-11-01 /pmc/articles/PMC10695638/ /pubmed/37907434 http://dx.doi.org/10.34067/KID.0000000000000260 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Nephrology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Brief Communication
Culek, Christopher T.
Nester, Carla M.
A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title_full A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title_fullStr A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title_full_unstemmed A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title_short A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase
title_sort nef precursor or benign counterpart: high prevalence of healthy subjects with antibody reactivity to the c3-convertase
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695638/
https://www.ncbi.nlm.nih.gov/pubmed/37907434
http://dx.doi.org/10.34067/KID.0000000000000260
work_keys_str_mv AT culekchristophert anefprecursororbenigncounterparthighprevalenceofhealthysubjectswithantibodyreactivitytothec3convertase
AT nestercarlam anefprecursororbenigncounterparthighprevalenceofhealthysubjectswithantibodyreactivitytothec3convertase
AT culekchristophert nefprecursororbenigncounterparthighprevalenceofhealthysubjectswithantibodyreactivitytothec3convertase
AT nestercarlam nefprecursororbenigncounterparthighprevalenceofhealthysubjectswithantibodyreactivitytothec3convertase

Ejemplares similares