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Molecular Phenotyping and Mechanisms of Myocardial Fibrosis in Advanced Chronic Kidney Disease

KEY POINTS: Myocardial fibrosis in hearts from patients with CKD is characterized by increased trimeric tensile collagen type I and decreased elastic collagen type III compared with hearts from hypertensive or healthy donors, suggesting a unique fibrotic phenotype. Myocardial fibrosis in CKD is driv...

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Detalles Bibliográficos
Autores principales: Narayanan, Gayatri, Halim, Arvin, Hu, Alvin, Avin, Keith G., Lu, Tzongshi, Zehnder, Daniel, Hato, Takashi, Chen, Neal X., Moe, Sharon M., Lim, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695648/
https://www.ncbi.nlm.nih.gov/pubmed/37858297
http://dx.doi.org/10.34067/KID.0000000000000276