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Crystal Modifications of a Cyclic Guanosine Phosphorothioate Analogue, a Drug Candidate for Retinal Neurodegenerations

In contribution to the pharmaceutical development of cyclic guanosine monophosphorothioate analogue cGMPSA as a potential active pharmaceutical ingredient (API) for the treatment of inherited retinal degenerations (IRDs), its neutral form (cGMPSA‐H) and salts of sodium (‐Na), calcium (‐Ca), ammonium...

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Detalles Bibliográficos
Autores principales: Pérez, Oswaldo, Schipper, Nicolaas, Leandri, Valentina, Svensson, Per H., Bohlin, Martin, Loftsson, Thorsteinn, Bollmark, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695737/
https://www.ncbi.nlm.nih.gov/pubmed/37877436
http://dx.doi.org/10.1002/open.202300141