Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome

Acute high-altitude (HA) exposure can induce several pathologies. Dexamethasone (DEX) can be taken prophylactically to prevent HA disease, but the mechanism by which it acts in this setting is unclear. We studied the transcriptome of peripheral blood mononuclear cells (PBMCs) from 16 subjects at low...

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Detalles Bibliográficos
Autores principales: Kumar, Rahul, Chanana, Neha, Sharma, Kavita, Palmo, Tsering, Lee, Michael H., Mishra, Aastha, Nolan, Kevin, Fonseca Balladares, Dara C., Mickael, Claudia, Gupta, Mohit D., Thinlas, Tashi, Pasha, Qadar, Graham, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695741/
https://www.ncbi.nlm.nih.gov/pubmed/37975243
http://dx.doi.org/10.1042/BSR20231561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695741/
https://www.ncbi.nlm.nih.gov/pubmed/37975243
http://dx.doi.org/10.1042/BSR20231561

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