Periportal hepatocyte proliferation at midgestation governs maternal glucose homeostasis in mice

The maternal liver is challenged by metabolic demands throughout pregnancy. However, hepatocyte dynamics and their physiological significance in pregnancy remain unclear. Here, we show in mice that hepatocyte proliferation is spatiotemporally regulated in each liver lobular zone during pregnancy, wi...

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Detalles Bibliográficos
Autores principales: Kozuki, Satoshi, Kabata, Mio, Sakurai, Satoko, Iwaisako, Keiko, Nishimura, Tomomi, Toi, Masakazu, Yamamoto, Takuya, Toyoshima, Fumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695921/
https://www.ncbi.nlm.nih.gov/pubmed/38049528
http://dx.doi.org/10.1038/s42003-023-05614-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695921/
https://www.ncbi.nlm.nih.gov/pubmed/38049528
http://dx.doi.org/10.1038/s42003-023-05614-3

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