A computational spatial whole-Cell model for hepatitis B viral infection and drug interactions

Despite a vaccine, hepatitis B virus (HBV) remains a world-wide source of infections and deaths. We develop a whole-cell computational platform combining spatial and kinetic models describing the infection cycle of HBV in a hepatocyte host. We simulate key parts of the infection cycle with this whol...

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Detalles Bibliográficos
Autores principales: Ghaemi, Zhaleh, Nafiu, Oluwadara, Tajkhorshid, Emad, Gruebele, Martin, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695947/
https://www.ncbi.nlm.nih.gov/pubmed/38049515
http://dx.doi.org/10.1038/s41598-023-45998-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695947/
https://www.ncbi.nlm.nih.gov/pubmed/38049515
http://dx.doi.org/10.1038/s41598-023-45998-0

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