Cargando…

CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration

Directed cell migration requires sustained cell polarisation. In migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub. Primary cilium-elicited signalling, and how it affects migration, remain however ill characterised...

Descripción completa

Detalles Bibliográficos
Autores principales: Atkins, Melody, Wurmser, Maud, Darmon, Michèle, Roche, Fiona, Nicol, Xavier, Métin, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695954/
https://www.ncbi.nlm.nih.gov/pubmed/38049397
http://dx.doi.org/10.1038/s41467-023-43645-w