Cargando…

CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration

Directed cell migration requires sustained cell polarisation. In migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub. Primary cilium-elicited signalling, and how it affects migration, remain however ill characterised...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atkins, Melody, Wurmser, Maud, Darmon, Michèle, Roche, Fiona, Nicol, Xavier, Métin, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695954/ https://www.ncbi.nlm.nih.gov/pubmed/38049397 http://dx.doi.org/10.1038/s41467-023-43645-w

Ejemplares similares

Intermingled cAMP, cGMP and calcium spatiotemporal dynamics in developing neuronal circuits
por: Averaimo, Stefania, et al.
Publicado: (2014)

Identification of novel target proteins of cGMP/cAMP signaling pathway using cGMP/cAMP capture compound mass spectrometry (CCMS)
por: Luo, Yan, et al.
Publicado: (2009)

Differential regulation of Paramecium ciliary motility by cAMP and cGMP
Publicado: (1988)

Biophysical Techniques for Detection of cAMP and cGMP in Living Cells
por: Sprenger, Julia U., et al.
Publicado: (2013)

IL-4 induces cAMP and cGMP in human monocytic cells
por: Dugas, B., et al.
Publicado: (1995)

Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration
por: Bombarda, Gabriela, et al.
Publicado: (2011)

cGMP and cAMP differentially regulate differentiation and function of brown adipocytes
por: Jennissen, Katja, et al.
Publicado: (2011)

Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum
por: Van Haaster, PJM, et al.
Publicado: (1983)

Differential regulation of platelet inhibition by cGMP- and cAMP-dependent protein kinases
por: Subramanian, Hariharan, et al.
Publicado: (2013)

Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii
por: Vo, Kim Chi, et al.
Publicado: (2022)

CLEC‐2‐dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP
por: Borgognone, A., et al.
Publicado: (2014)

Therapeutic Implications for PDE2 and cGMP/cAMP Mediated Crosstalk in Cardiovascular Diseases
por: Sadek, Mirna S., et al.
Publicado: (2020)

Compartmentalised cAMP signalling in the primary cilium
por: Paolocci, Ester, et al.
Publicado: (2023)

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides
por: Werner, Katharina, et al.
Publicado: (2011)

Quantification of cAMP and cGMP analogs in intact cells: pitfals in enzyme immunoassays for cyclic nucleotides
por: Werner, Katharina, et al.
Publicado: (2011)

Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II
por: Mokni, Walid, et al.
Publicado: (2010)

Effects of thoracic epidural analgesia on plasma cAMP and cGMP levels in patients with heart failure
por: Li, Qing-Shu, et al.
Publicado: (2013)

Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes
por: Pavlaki, Nikoleta, et al.
Publicado: (2018)

Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
por: Calamera, Gaia, et al.
Publicado: (2022)

The NO/cGMP pathway inhibits transient cAMP signals through the activation of PDE2 in striatal neurons
por: Polito, Marina, et al.
Publicado: (2013)

Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase
por: Friebe, Andreas, et al.
Publicado: (2015)

Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain
por: Scheib, Ulrike, et al.
Publicado: (2018)

Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk
por: Kurelic, Roberta, et al.
Publicado: (2021)

Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia
por: Selli, Anders Lund, et al.
Publicado: (2022)

Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein
por: Werel, Laura, et al.
Publicado: (2023)

Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP
por: Selli, Anders L., et al.
Publicado: (2021)

Phosphodiesterase 4 inhibitors and db-cAMP inhibit TNF-α release from human mononuclear cells. Effects of cAMP and cGMP-dependent protein kinase inhibitors
por: Hichami, A., et al.
Publicado: (1996)

Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration
por: Stoufflet, Julie, et al.
Publicado: (2020)

CSF Concentrations of cAMP and cGMP Are Lower in Patients with Creutzfeldt-Jakob Disease but Not Parkinson's Disease and Amyotrophic Lateral Sclerosis
por: Oeckl, Patrick, et al.
Publicado: (2012)

The G Protein Coupled Receptor 3 Is Involved in cAMP and cGMP Signaling and Maintenance of Meiotic Arrest in Porcine Oocytes
por: Yang, Cai-Rong, et al.
Publicado: (2012)

cGMP and cAMP pathways rearrange ARHGAP17 and ARHGEF6 protein complexes to control Rac1 in platelets
por: Nagy, Zoltan, et al.
Publicado: (2015)

Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways
por: Anwar, Mohammad A., et al.
Publicado: (2018)

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium
por: Tschaikner, Philipp, et al.
Publicado: (2020)

The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding
por: Kim, Jeong Joo, et al.
Publicado: (2011)

NO-donors induce cross talk between cGMP and cAMP in signalling to human atrial L-type Ca(2+) current
por: Rozmaritsa, Nadiia, et al.
Publicado: (2011)

Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides
por: Wolter, Sabine, et al.
Publicado: (2011)

Levosimendan Relaxes Pulmonary Arteries and Veins in Precision-Cut Lung Slices - The Role of K(ATP)-Channels, cAMP and cGMP
por: Rieg, Annette D., et al.
Publicado: (2013)

CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats
por: Cai, Ying-Lan, et al.
Publicado: (2015)

Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy
por: Brescia, Marcella, et al.
Publicado: (2020)

Inhibition of Phosphodiesterase 2 Ameliorates Post-Traumatic Stress–Induced Alcohol Intake Disorder by Regulating cAMP/cGMP Signaling
por: Pan, Xiaoyu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_46tae8m4f2elritc67f7eq18ls