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Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases

BMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis, growth and repair. They act by promoting the deposition of structural extracellular matrix proteins and by controlling the activity of matricellular proteins and TGF-β superfamily growth factors. They have also been imp...

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Detalles Bibliográficos
Autores principales: Vadon-Le Goff, Sandrine, Tessier, Agnès, Napoli, Manon, Dieryckx, Cindy, Bauer, Julien, Dussoyer, Mélissa, Lagoutte, Priscillia, Peyronnel, Célian, Essayan, Lucie, Kleiser, Svenja, Tueni, Nicole, Bettler, Emmanuel, Mariano, Natacha, Errazuriz-Cerda, Elisabeth, Fruchart Gaillard, Carole, Ruggiero, Florence, Becker-Pauly, Christoph, Allain, Jean-Marc, Bruckner-Tuderman, Leena, Nyström, Alexander, Moali, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696041/
https://www.ncbi.nlm.nih.gov/pubmed/38049428
http://dx.doi.org/10.1038/s41467-023-43401-0