Cargando…
Carboxypeptidase A4 negatively regulates HGS-ETR1/2-induced pyroptosis by forming a positive feedback loop with the AKT signalling pathway
Pyroptosis, a mode of inflammatory cell death, has recently gained significant attention. However, the underlying mechanism remains poorly understood. HGS-ETR1/2 is a humanized monoclonal antibody that can bind to DR4/5 on the cell membrane and induce cell apoptosis by activating the death receptor...
Autores principales: | Wang, Luoling, Deng, Rilin, Chen, Shuishun, Tian, Renyun, Guo, Mengmeng, Chen, Zihao, Zhang, Yingdan, Li, Huiyi, Liu, Qian, Tang, Songqing, Zhu, Haizhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696061/ https://www.ncbi.nlm.nih.gov/pubmed/38049405 http://dx.doi.org/10.1038/s41419-023-06327-5 |
Ejemplares similares
-
The dual functions of KDM7A in HBV replication and immune microenvironment
por: Yang, Di, et al.
Publicado: (2023) -
RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growth
por: Wang, Cong, et al.
Publicado: (2022) -
Regulation of PKR-dependent RNA translation inhibition by TRIM21 upon virus infection or other stress
por: Li, Huiyi, et al.
Publicado: (2023) -
HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
por: Pukac, L, et al.
Publicado: (2005) -
CARBOXYPEPTIDASE : III. THE ESTIMATION OF CARBOXYPEPTIDASE AND PRO-CARBOXYPEPTIDASE
por: Anson, M. L.
Publicado: (1937)