Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age

Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early post-natal/juvenile (<2 m.o.) Tam induction, but age-related neurodegeneration and aging studies can require Cre induction in older mice (>12 m.o.)....

Descripción completa

Detalles Bibliográficos
Autores principales: Kellogg, Collyn M., Pham, Kevin, Ko, Sunghwan, Cox, Jillian E.J., Machalinski, Adeline H., Stout, Michael B., Sharpe, Amanda L., Beckstead, Michael J., Chucair-Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696116/
http://dx.doi.org/10.1016/j.isci.2023.108413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696116/
http://dx.doi.org/10.1016/j.isci.2023.108413

Ejemplares similares