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Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age
Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early post-natal/juvenile (<2 m.o.) Tam induction, but age-related neurodegeneration and aging studies can require Cre induction in older mice (>12 m.o.)....
Autores principales: | Kellogg, Collyn M., Pham, Kevin, Ko, Sunghwan, Cox, Jillian E.J., Machalinski, Adeline H., Stout, Michael B., Sharpe, Amanda L., Beckstead, Michael J., Chucair-Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696116/ http://dx.doi.org/10.1016/j.isci.2023.108413 |
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