The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy

Sphingolipids (SL) represent a structurally diverse class of lipids that are central to cellular physiology and neuronal development and function. Defects in the sphingolipid metabolism are typically associated with nervous system disorders. The C4-dihydroceramide desaturase (DEGS1) catalyzes the co...

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Detalles Bibliográficos
Autores principales: Hülsmeier, Andreas J., Toelle, Sandra P., Bellstedt, Peter, Wentzel, Christian, Bahr, Angela, Kolokotronis, Konstantinos, Hornemann, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Lipid Metabolism and Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696257/
http://dx.doi.org/10.1016/j.jlr.2023.100464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696257/
http://dx.doi.org/10.1016/j.jlr.2023.100464

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