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Local delivery of EGFR(+)NSCs-derived exosomes promotes neural regeneration post spinal cord injury via miR-34a-5p/HDAC6 pathway

Spinal cord injury (SCI) causes severe axon damage, usually leading to permanent paraparesis, which still lacks effective regenerative therapy. Recent studies have suggested that exosomes derived from neural stem cells (NSCs) may hold promise as attractive candidates for SCI treatment. Epidermal Gro...

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Detalles Bibliográficos
Autores principales: Qin, Tian, Li, Chengjun, Xu, Yan, Qin, Yiming, Jin, Yuxin, He, Rundong, Luo, Zixiang, Zhao, Jinyun, Duan, Chunyue, Lu, Hongbin, Cao, Yong, Hu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696309/
http://dx.doi.org/10.1016/j.bioactmat.2023.11.013