Cargando…

Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism

Macrophages clear infections by engulfing and digesting pathogens within phagolysosomes. Pathogens escape this fate by engaging in a molecular arms race; they use WxxxE motif–containing “effector” proteins to subvert the host cells they invade and seek refuge within protective vacuoles. Here, we def...

Descripción completa

Detalles Bibliográficos
Autores principales: Anandachar, Mahitha Shree, Roy, Suchismita, Sinha, Saptarshi, Boadi, Agyekum, Katkar, Gajanan D., Ghosh, Pradipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696401/
http://dx.doi.org/10.1016/j.jbc.2023.105390