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Missing a “Missing Self” Mechanism: Modeling and Detection of Ly49 Expression in Canine NK Cells

NK cells are a key focus in immuno-oncology, based on their ability to eliminate malignant cells without prior sensitization. Dogs are valuable models for translational immunotherapy studies, especially for NK cells, where critical species differences exist between mice and humans. Given that the me...

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Detalles Bibliográficos
Autores principales: Gingrich, Alicia A., Razmara, Aryana M., Gingrich, Phillip W., Rebhun, Robert B., Murphy, William J., Kent, Michael S., Brown, C. Titus, Siegel, Justin B., Canter, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696421/
https://www.ncbi.nlm.nih.gov/pubmed/37971282
http://dx.doi.org/10.4049/immunohorizons.2300092