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Top-Down Proteomics and the Challenges of True Proteoform Characterization
[Image: see text] Top-down proteomics (TDP) aims to identify and profile intact protein forms (proteoforms) extracted from biological samples. True proteoform characterization requires that both the base protein sequence be defined and any mass shifts identified, ideally localizing their positions w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696603/ https://www.ncbi.nlm.nih.gov/pubmed/37937372 http://dx.doi.org/10.1021/acs.jproteome.3c00416 |