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SNORA56-mediated pseudouridylation of 28 S rRNA inhibits ferroptosis and promotes colorectal cancer proliferation by enhancing GCLC translation

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies and is characterized by reprogrammed metabolism. Ferroptosis, a programmed cell death dependent on iron, has emerged as a promising strategy for CRC treatment. Although small nucleolar RNAs are extensively involved in carcino...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Bian, Zhixuan, Wang, Xinyue, Niu, Na, Liu, Li, Xiao, Yixuan, Zhu, Jiabei, Huang, Nan, Zhang, Yue, Chen, Yan, Wu, Qi, Sun, Fenyong, Zhu, Xiaoli, Pan, Qiuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696674/
https://www.ncbi.nlm.nih.gov/pubmed/38049865
http://dx.doi.org/10.1186/s13046-023-02906-8